Analysis of fatty acid composition content in the plant components of antidiabetic herbal mixture by GC-MS

Medical plants and their combinations due to the wide range of biologically active substances can influence on various links pathogenetic mechanism development diabetes mellitus its complications. One such is an anidiabetic herbal mixture ( Urtica dioica L. leaf, Rosa majalis fruits, Vaccinium myrtillus Mentha piperita herb Taraxacum officinale roots) with established hypoglycemic, hypolipidemic, antioxidant, hepatoprotective, pancreatoprotective activity in previous pharmacological study vivo. Thus, aim this was identify establish fatty acid content plant components antidiabetic mixture. Fatty acids were separated by validated method gas chromatography-mass spectrometry after conversion into methyl esters. The result showed that leaf contain 12 (8 saturated, 2 monounsaturated polyunsaturated), fruits roots – 13 (9 polyunsaturated) 14 (10 polyunsaturated). predominant long-chain carboxylic all raw materials unsaturated acids, 55.3% 64.7% 60.5% 64.3% 51.7% roots. This indicates feasibility including each component order form anticholesterolemic, anti-inflammatory, immunomodulatory neuroprotective activity, high omega-3, omega-6 omega-9 acids.